Telomere - Wikipedia

Google: lengthen telomeres naturally Telomere - Wikipedia Telomeres are repetitive nucleotide sequences located at the termini of l...

Showing posts with label telomeres supplements. Show all posts
Showing posts with label telomeres supplements. Show all posts

Tru Niagen Chromadex May Protect Telomeres

New preclinical study finds boosting NAD+ with nicotinamide riboside alleviated telomere damage, providing protective effect to DNA strands

LOS ANGELES--(BUSINESS WIRE)-- ChromaDex Corp. (NASDAQ:CDXC) today highlighted a new study published in The European Molecular Biology Organization Journal looking at the effect of nicotinamide riboside (NR) on maintaining telomeres, the protective regions at the end of DNA strands. This study is the first to show that by increasing NAD+, NR helped protect telomeres which are important in addressing life-threatening telomere-related diseases, paving the way for future clinical research. The study was conducted by investigators at the National Institute on Aging (NIA) and the National Cancer Institute (NCI), parts of the National Institutes of Health (NIH). The role of ChromaDex in this study was to provide NR through the ChromaDex External Research Program (CERP). All other aspects of the study, including analysis of the results and writing of the manuscript were conducted independently by the authors.

“Telomere attrition is recognized as one of the nine hallmarks of aging and it is well accepted that telomeres play a significant role in aging and many age-related health declines,” said Frank Jaksch, Co-Founder & Executive Chairman of ChromaDex. “These preliminary results suggest that NR can impact telomere function.”

Telomeres are “caps” at the end of chromosomes that protect DNA from getting worn away as cells replicate. Telomeres degrade and shorten with age and can become excessively damaged in certain genetic diseases, as well as from lifestyle factors such as smoking, poor diet, and chronic stress. Shortening of telomeres is associated with the symptoms of aging, heart disease, DNA damage and uncontrolled cell replication, which can lead to cancer.

Dyskeratosis congenita (DC) is a disease of pre-mature aging, which occurs due to a deficiency of telomere maintenance proteins. Without normal telomere function, DC presents with early-onset, life-threatening symptoms of aging in the skin, bone marrow, lungs, heart and brain.

In this recently published study, scientists examined connective tissue cells from DC patients and found that, not only were their telomeres significantly damaged, but they were also depleted in NAD+. Likewise, these scientists produced “telomere-depleted” mice by inactivating a gene for telomerase, the enzyme that extends telomeres. These mice also had low NAD+ levels.

The scientists then supplemented the cells and mice with NR. NR works by raising levels of NAD+, an important regulator that is known to naturally decline with age. In this study NR increased NAD+ levels, reduced signs of telomere damage, promoted cell growth and prevented senescence (cellular aging) in the DC cells.

These promising findings suggest that NAD+ repletion plays a role in maintaining healthy telomere function; however, additional research is needed.

While congenital telomere disorders like DC are rare, telomere dysfunction is implicated in signs and symptoms of normal human aging. Whether NR could play a role in supporting various aging organs is currently under investigation in dozens of human trials.

ChromaDex, the exclusive licensee of Dr. Charles Brenner’s patented NR, has invested over $35 million in investigating, manufacturing and offering NR in the form of Niagen and has secured more than 20 patents. ChromaDex has demonstrated the safety and efficacy of Niagen in 11 published human trials (and over 20 additional ongoing studies further evaluating its safety and efficacy) and has achieved government regulatory acceptance in the United States, Canada, the European Union, and Australia.

For additional information about ChromaDex, please visit www.chromadex.com.

About ChromaDex:

ChromaDex Corp. is a science-based integrated nutraceutical company devoted to improving the way people age. ChromaDex scientists partner with leading universities and research institutions worldwide to discover, develop and create solutions to deliver the full potential of NAD and its impact on human health. Its flagship ingredient, NIAGEN® nicotinamide riboside, sold directly to consumers as TRU NIAGEN®, is backed with clinical and scientific research, as well as extensive IP protection. TRU NIAGEN® is helping the world AGE BETTER®. ChromaDex maintains a website at www.chromadex.com to which ChromaDex regularly posts copies of its press releases as well as additional and financial information about the Company.

Forward-Looking Statements:

This release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities and Exchange Act of 1934, as amended, including statements related to whether NR helps improve telomere dysfunction and whether NAD+ repletion will play a role in maintaining healthy telomere function in humans. Statements that are not a description of historical facts constitute forward-looking statements and may often, but not always, be identified by the use of such words as "expects," "anticipates," "intends," "estimates," "plans," "potential," "possible," "probable," "believes," "seeks," "may," "will," "should," "could" or the negative of such terms or other similar expressions. More detailed information about ChromaDex and the risk factors that may affect the realization of forward-looking statements is set forth in ChromaDex's Annual Report on Form 10-K for the fiscal year ended December 31, 2019 as amended, ChromaDex's Quarterly Reports on Form 10-Q and other filings submitted by ChromaDex to the SEC, copies of which may be obtained from the SEC's website at www.sec.gov. Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof, and actual results may differ materially from those suggested by these forward-looking statements. All forward-looking statements are qualified in their entirety by this cautionary statement and ChromaDex undertakes no obligation to revise or update this release to reflect events or circumstances after the date hereof.

ChromaDex Media Contact:
Alex Worsham, Senior Director of Global Corporate Communications
310-388-6706 ext. 689

ChromaDex Investor Relations Contact:
Brianna Gerber, Vice President of FP&A and Investor Relations
949-419-0288 ext. 127

Source: ChromaDex Corporation

Support Telomere Length

The results confirm and expand previous work on the genetics of telomere length, while acknowledging that the effect of lithium may be limited to a small number of cells in the human body, rather than the entire body. Although ageing is a complex process, we have found a clear - and well-defined - biomarker of ageing at the cellular level: the length of telomerase, the protective layer of the cell. While researchers are linking aging and disease, the breed is in the process of understanding the factors that determine the length of the teloreceptor. We note that our results provide the first direct evidence of the role of lithium in aging, which has been poorly understood at both cellular and molecular levels. Sources: 7, 9, 14, 16
In our study, current family and social support had a positive relationship with telomere length, but unsurprisingly not against the historical burden of childhood stress. However, this small study provides a good basis for recent research on the role of stress in the development of teloreceptors and the effects of lithium on telomerase. Alternatively, social support may play a protective role by buffering the effects of stress on telomere length, which shortens the rate of cell replication, and mitigating the negative effects of stress on telomeres. Sources: 5, 8
Understanding how telomere length is regulated is crucial to realizing the potential benefits of lithium in the development of teloreceptors and other cell types, "Rivera said. We focus on the role of stress and social support in supporting telitere structure and function in human health. Sources: 11, 14
On the surface, it seems desirable to strike a balance between maintaining and increasing telomere length and telomerase activity. Since telomeres can shorten in the context of aging and be maintained and prolonged by telomerase, it is logical that interventions modulating the telomerasing duo of teloreceptors represent a chance to prevent, delay, or minimize the degenerative diseases associated with age. Sources: 6, 11
However, it is unwise to say that increasing telomere length by pharmacological or nutraceutical means is advisable, as it can cause undesirable side effects. Sources: 6
Matt Kaeberlein, who studies the molecular basis of aging at the University of Washington, says: "By measuring telomere length in the blood, we are actually reporting a well-functioning immune stem cell. When we measure the length of a single cell, such as a blood stem cell, we need to think about how much work the stem cell does and how often it is supported by a particular tissue. Sources: 1, 2
Analysis of telomere structure, function and biology will be crucial to clarify the role of lithium in maintaining telomere length and structure. Vitamins C and E can limit the effects of the shortening of telotechnologies, such as those found in blood stem cells, on short- and long-term telomeres. On the other hand, the critical telomerase length can lead to a fusion of the chromosomes by the NHEJ mechanism or to the telomeres uncapping. Future longitudinal studies to assess the effect of lithium on age - the associated disease risk is likely to be based on confirmation that gene transcripts are the primary mediator in lithium tele - will prolong the effects on teloneurons. Sources: 3, 9, 12
Finally, it should be borne in mind that genetic factors only make up a small proportion of the overall effect of lithium on telomere length and structure. It is difficult to interpret the effects of other factors such as age - specific changes in telomerase activity, given the age of each individual. Sources: 3, 6
Although it can take months or years for telomeres to change significantly, the authors write, "we should focus on maintaining healthy habits rather than being obsessed with telomerase activity at a certain point in time or telomere length," they write. It seems to be a matter of time before you stay healthy, not if you get an illness or actually die, but rather when. Sources: 15, 17
Previous laboratory and epidemiological findings support several plausible biological pathways, including changes in cell and immune function [22], and maternal stress during pregnancy is associated with shorter offspring telomeres [23]. However, this work does not cover cellular aging, such as telomerase length, as a marker. Finally, the study did not include an analysis of newborn telomere length, but was conducted in mammals, particularly in humans, which have little or no somatic telomerase production. Sources: 0, 8, 18
The current data show the importance of telomere length as a biomarker of cellular aging in the development of Alzheimer's disease. We are now studying dementia sufferers and seeing how various ways of reducing their stress can improve the biomarkers of ageing, including telomerase length. Sources: 8, 17
The possibility of offering telomere length as part of a genetic test is intriguing, because the genetic material that protects telomeres is protected by telomerase, the enzyme responsible for repairing the chromosomes in the cell. Sources: 13
Comparative genomic work has shown that lithium can moderate the expression of genes that control telomere length, and this may be a mechanism by which lithium prolongs telomeres in patients with bipolar disorder. This novel telomerase loop mechanism implies that progressive teliter shortening can affect cell physiology and age-related diseases, such as aging, as telomeres become incurably short and trigger DNA damage signals. Lifestyle is an important factor in telomyelitis, a disease of the heart, brain and spinal cord, so length could be an important determinant of a patient's long-term wellbeing. It might explain how some of us age more or less than others, with decisions we make every day. 

Cited Sources

Fish oil — Not so fast! This Omega-3 is 800% better…

This post contains affiliate links. Click here for the full disclosure statement.

800% Better Than Fish Oil

The first REAL solution to aging has done
wonders for my patients, and now it can help you…

• “Re-program” your cells to feel a whole generation younger

• Enjoy the best cholesterol and triglycerides levels you’ve had in years

• Ease pain and discomfort so you walk, bend and flex freely again

• Reduce your risk of a serious heart “disaster “ by 50%

• Supercharge your mind and memory no matter your age

• Have healthy blood sugar

Sound good? Then…

Health Conscious Reader,
Dr. Sears' speech
Let me tell you how this secret is helping my patients look and feel 10, 20 even 30 years younger — and now it can do the same for you.
The story starts with three words that stunned an audience of doctors at the World Congress on Anti-Aging Medicine.

What did I tell my fellow doctors that can help you retain all the powers of your youth?

Save your telomeres!

A Nobel Prize... research at Harvard, Yale and USC... and the journals Nature, Cell, Lancet, Science and Nutrition Review all confirm that the strongest indicator of how quickly you age is the health and length of protective caps at the end of each strand of your DNA called telomeres.

And now, I’ve discovered a new omega-3 secret that’ll help you boost your telomeres... reverse the signs and symptoms of aging... and regain all the qualities of your youth — no matter your age.

How my patients got 14 years
“younger” on average

Recently, I concluded what I call a “grand experiment” at my clinic.
youth chart

One hundred of my patients received my latest anti-aging breakthroughs, including the “telomere techology” you’ll read about in this letter — and the improvements in their health and aging were simply amazing!

At the beginning of the study, I measured the “age quotient” of 12 areas of their health such as their hearts, brains, lungs, livers, arteries, muscles and yes, telomere length.

After 30 months, virtually all of these measures improved — meaning all of these patients looked and felt years younger.

In fact, as this chart shows, they averaged a 14-year improvement in their “youth quotient”.

This means, if they were 58 years old, they felt like they were 44. And some felt 20 years or more younger — and their medical tests prove it.

Now, for the first time, you too can enjoy a “young again” heart, brain, arteries, muscles, telomeres and more. How? With the telomere-boosting breakthrough I’ll tell you about.

The secret to “young again” living
starts deep within your cells

Telomeres are the tiny bindings at the end of each strand of DNA in your chromosomes. They stop your DNA from fraying, like the plastic tips at the end of shoelaces.

Each cell in your body has 92 telomeres. They are like a ticking biological clock because your cells have a fixed lifespan.

Each time your cells divide, a tiny bit of telomere gets used up. Over time, your telomeres get shorter and shorter until your DNA can no longer make correct copies.

This process happens slowly, and it makes your cells act older and weaker. If 70-80% of your telomeres erode away, your cells can become permanently damaged.

After 50 or so divisions, the telomeres can no longer protect your chromosomes so your cells die.

The result? Many of today’s most widespread health conditions, including premature aging, are associated with shorter telomeres.

But don’t just take my word for it. Here’s what Harvard doctors say...

Harvard doctors warn that when your telomeres become critically short, they activate the p53 shutdown gene — putting your cells into “the death spiral”

Over time, your telomeres get so short they can’t protect your DNA.

When your cells divide, new cells are defective — so you begin to develop the signs of disease and old age. Critically short telomeres activate the shutdown p53 gene, setting in motion what Harvard researchers call a “death spiral” (Sahin, Nature 2011).

In fact, we now have a lot more science backing up the damage of shorter telomeres...
  • Gerontology reports that shorter telomeres cause dysfunction in your heart and artery cells.1
  • Journal of Clinical Endocrinology & Metabolism warns that if your telomeres get shorter, you are more prone to obesity and a blood sugar or blood pressure disaster.2
  • Journal of Internal Medicine warns that shorter telomeres mean an earlier death, regardless of age, sex or lifestyle.3
  • Lancet adds that “Short telomeres cause us to die of old age.”
In fact, shorter telomeres dramatically boost your risk of serious diseases. They’ve been linked to a 300% increase of death by heart disease and a 800% higher death rate from infectious diseases.4

But what if you supercharge your telomeres? Your cells could act young again!

That’s what I’m doing for my patients and myself — and now, you can feel younger, too.

Using what I call “telomere technology,” I’ve had some patients reverse 10, 20 or even 30 years of the signs and symptoms of aging.
  • Helen, age 85, recently broke her age group record in the marathon
  • Bill, age 64, has the lung power of a 39-year-old
  • Michael, age 61, has the brain aptitude of a 29-year-old
  • Shelby, age 45, has more youthful, more elastic, more supple skin measured by a Cutometer
  • And I’m 60, but the true “biological age” of my heart is age 22, my brain, age 35 and my lungs, age 18.
These age references are based on decades of research which show how biologically young a person is, based on a comprehensive set of physical tests, not chronological age.

Our secret is boosting telomeres, and now there’s a new omega-3 breakthrough that can help you do just that — Omega Rejuvenol.

What can happen if you make your telomeres longer and healthier with Omega Rejuvenol? Some amazing things as you’ll now see...

10 remarkable health and anti-aging benefits that are yours IF you make your telomeres longer

Research shows that with longer telomeres, you have a better chance of avoiding almost every age-related health concern... plus you can look and feel a decade or more younger.

The proof? Longer telomeres can help...

1. Razor sharpen your mind. The famous Nurses’ Health Study, published in Neuroscience Letter, looked at telomeres of 2,000 women. Those with longer telomeres had less cognitive decline. 5 In addition, Neurobiology of Aging reports longer telomeres protect the brain from aging and dementia. 6

In fact, each unit increase in telomere length is like your brain acting a year younger. Picture yourself mentally “outshining” those who are 20, even 30 years younger than you!

2. Chase away the blues. PLoS One reports that with longer telomeres, you can stay happy and energized. Feeling “down” is now associated with cell aging. The longer your telomeres, the less likely you are to suffer from the blues. 7

What’s more, Health Psychology adds that people with longer telomeres are happier and have a better outlook on life. 8

3. Supercharge your heart. Ageing Research Reviews notes that longer telomeres mean “younger acting” cells — and this means a reduced risk of cardiovascular problems. 9 In fact, people with the longest telomeres have a 54% lower risk of serious heart problems. 10

4. Slim your body. Journal of Clinical Endocrinology & Metabolism reports that telomere length affects your weight. A study found that obese children have telomeres that are nearly 24% shorter than non-obese children. 11

5. Sharpen your eyes. The Journals of Gerontology report that longer telomeres reduce your risk of serious eye conditions by 50%. And people with vision problems who had longer telomeres had less severe cases than those with shorter telomeres. 13

6. Support healthy blood sugar. Diabetic Medicine reports people with blood sugar problems have significantly shorter telomeres than people without it. The longer your telomeres, the better chance you have of avoiding out-of-control blood sugar. 14

7. Keep your teeth and gums healthier. Free Radical Biology and Medicinenotes that people with gum problems have 23% shorter telomeres. Yet those with longer telomeres have no gum problem and lower markers of inflammation. This is important because one indicator of inflammation in your body is gum and teeth problems. 15

8. Give you nights and nights of sounder sleep. In China, researchers looked at the immune system of people who had trouble sleeping compared with people who slept normally. The ratio of white blood cells with longer telomeres was significantly higher in healthy people than for people with sleep problems. 16

9. Keep your joints pain free and mobile. Autoimmunity Reviews reports that telomeres appear to shorten faster for people with serious joint pain problems. What’s more, longer telomeres are associated with lower risk of these problems. 17

10. Look years younger with more youthful skin. Did you know that even for identical twins, the one with longer telomeres always looks younger than the twin with shorter telomeres? The twins who looked younger than their true age had better health and longer survival rates than their older looking siblings.

Fortunately, we now have the ability to influence the length of these tiny genetic clocks, your telomeres.

You can have younger-acting cells and help avoid age-related problems by maintaining your telomere length.

The best way to boost your telomeres? Taking Omega Rejuvenol every day.
What makes it my No. 1 omega-3 age-fighting supplement?

Results don’t lie. With Omega Rejuvenol...
Milo hiked eight miles at 7,000 and 8,000 feet!

“Thanks to Dr. Sears and Omega Rejuvenol, I feel the best I have in decades. My bone density is that of a 20-year-old... my lung capacity has improved significantly (I recently hiked 8 miles at 7,000 and 8,000 feet with no problems)... my blood sugar is normal... my cholesterol levels are within normal ranges... and my body fat is 20% so I’m now wearing slim shirts and slim jeans.” —Milo H.

Mark’s memory is back at age 30-levels!
“I was worried when I started blanking out on things that used to be routine. All those ‘senior moments’ started too young. But they suddenly stopped when I started taking Omega Rejuvenol. Now, I feel my focus and memory are back at age 30-levels.” —Mark K., Jupiter, FL


Kim’s knees stopped hurting!
“After taking Omega Rejuvenol, my knees stopped clacking, and I can literally skip down the stairs. Thank you so much.” —Kim L., Malaysia

Kerry looks years younger!
Omega Rejuvenol works really well for me. Although I have fairly good skin for my age, this has certainly made a difference.
I get compliments all the time about my skin and no one knows my real age. They always think I’m much younger than my years. Really fantastic. Thank you, Dr. Sears.” —Kerry S., New Zealand
Neville got a second chance at living!
“I was going out the back door, fast... [with so many health challenges and pain]. With Omega Rejuvenol, I don’t have any more pain.

I feel a lot better, am not so tired and hope to live longer than they have predicted. Keep up the good work.” —Neville A., Queensland, Australia

The telomere-boosting power of a special form
of omega-3s helps you feel a whole
generation younger

I’m one of the first medical doctors to use “telomere technology” to help my patients’ telomeres get longer and healthier — and I am one of the first doctors in the world licensed to administer TAT-2, the first telomere activator.

But good as TAT-2 is, it’s very expensive and out of the reach of most of my patients and the general public.

So I’ve searched the medical research to see if any special nutrients or vitamins that boost telomeres and activate telomerase (the enzyme that rebuilds telomeres) were more easily accessible to all.

I found 123 compounds that alter telomere biology — and the best is...

Omega-3 fatty acids, but not the ordinary kind

For years I’ve known the healing power of omega-3 fatty acids, but now we know why they are so potent for fighting aging and boosting health.

Doctors at Ohio State University and U.C. San Francisco wanted to see if taking omega-3 supplements could affect the rate at which telomeres shorten.

In a study published in Brain, Behavior, and Immunity, 106 healthy, sedentary, middle-aged, older adults were given a placebo... a low dose of 1.5 grams/day EPA and DHA, the most active ingredients in omega-3... or a high dose of 2.5 grams/day of EPA and DHA for four months.

Telomere length was measured at the beginning and end of the study. The results? Shocking!

The telomeres of those taking the omega-3s did notshorten but actually increased in length.


Those taking the low dose omega-3s saw telomere length increase by 21 base pairs, and those taking high dose omega-3s increased telomere length by 50 base pairs.

Those taking the placebo? They saw a decrease in telomere length by 43 base pairs! 18

This study reveals an important point: If you do nothing, your telomeres will shorten with age... you will age faster... and you will be more vulnerable to many aging health ailments.

But now, you can unleash the full power of telomere-boosting omega-3s

You may be thinking, “Okay I need more omega-3s to boost my telomeres and feel younger, so I’ll take more fish oil.”

Not so fast!

We now know that...
  • Fish oil FAILS to deliver enough of the most important telomere-boosting omega-3, DHA, so you don’t get its full youth-enhancing power.
  • Fish oil FAILS to get into your cells quickly enough, so you don’t get all the age-fighting power you need.
  • Many fish oils FAIL to deliver the omega-3 listed on the bottle labels, so you end up wasting your money on next to nothing.

For these reasons, the first key ingredient in Omega Rejuvenol is...

The most powerful omega-3 I’ve ever found to help you reclaim your youth.

I tell my patients eating fish or taking ordinary omega-3 fish oil is not good enough if you want the full, youth-enhancing power of omega-3s.

That’s why I recommend krill oil, and that’s why it’s the first key ingredient in Omega Rejuvenol.

As you may know, krill are tiny shrimp-like creatures that swim in huge biomasses in the pure, cold waters near the South Pole.

But what you may not know is, krill is the original source of omega-3s, offering you a much more POTENT source of health-boosting, age-fighting DHA and EPA.
Krill is superior because its omega-3s are stored in a much different biological form than fish oil.

The omega-3s (especially DHA) in krill oil are bound to a fat called a phospholipid — which is much simpler to digest than the triglyceride or ethyl ester form found in fish oil.

The result? Krill oil is able to penetrate into nearly EVERY cell in your body — and even into your cells’ power plants called mitochondria — in a far better way than fish oil.

Tests prove it: Krill delivers 30%
more omega-3s than fish oil!

Nutrition Research published a study that documents the power of krill oil. In this study, krill oil, fish oil and olive oil were compared to see which one raised omega-3 levels higher.

krill vs fish

Seventy six overweight and obese people took 2 grams of krill oil, fish oil or olive oil every day for four weeks — then their omega-3 levels were measured.
The results were eye-opening to say the least!
  • Those taking olive oil saw their omega-3s rise 2.9%.
  • Those taking fish oil saw their omega-3s rise 131.8%.
  • Yet those taking krill oil saw their omega-3s skyrocket 178.4%!
That’s 30% MORE omega-3s absorbed from krill oil than from fish oil! 19

Now you see why, to boost telomeres in my patients and in myself, I only recommend krill oil in Omega Rejuvenol — and now you can do the same!

But that’s not all. Wait until you see what krill oil can do to help you enjoy the best cholesterol and triglycerides in your life... 800% better than fish oil!

Peter’s LDL cholesterol is 122, and his triglycerides are 135. What’s his secret?
“There is no one I trust more concerning my health and nutrition than Dr. Sears.
Since I’ve been taking Omega Rejuvenol, my LDL cholesterol is at a healthy 122. And my triglycerides are at an incredible 135.” — Peter

Why such great results with Omega Rejuvenol?

In an impressive clinical study, the superiority of krill oil over fish oil was clear, especially for healthier cholesterol and triglycerides.

In a double-blind, randomized clinical study, people aged 18–35 who were suffering from cholesterol and triglycerides concerns took 3 grams of krill oil, fish oil or a placebo every day for 12 weeks.

In every case, krill out soundly outperformed fish oil!
For example...
  • Krill oil worked 800% better than fish oil for healthier LDL cholesterol.
  • Krill oil worked 800% better than fish oil for healthier triglycerides.
  • Krill oil worked 300% better than fish oil for total cholesterol.
  • Krill oil worked 1,400% better than fish oil for raising HDL “good” cholesterol.20
Bottom line: With the krill oil found in Omega Rejuvenol...

You can enjoy a stronger heart and great cholesterol and triglycerides numbers

I tell my patients Omega Rejuvenol can give them a “cardio boost,” and it can do the same for you.

That’s because of its rich EPA/DHA omega-3 content.

EPA/DHA can mean a stronger heart, and this is proven in research.

Circulation journal reports that in Japan, serious heart problems are at ONE HALF the level of Western countries like the U.S.

Why? Because of the high level of omega-3 consumption in Japan.

What’s more, the American Journal of Clinical Nutrition adds that people taking 250 mg a day of DHA/EPA omega-3’s reduced cardiovascular death risk by 36%. 21

But that’s not all. Omega Rejuvenol also gives you something rarely seen in any omega-3 supplement, one vital for your vision, memory and blood sugar...

“I’m close to 80 but feel like I’m 60 again!”

“The first day I took Omega Rejuvenol, I noticed a surge of everything. It was like I dropped years off my age. I am close to 80 but feel more like I am 60.

“At that age, I was still a man to be taken seriously, by men and women. And I can tell you that is a good feeling to have at any age.”— Homer

Nick is getting compliments galore thanks to Omega Rejuvenol!

“My body was very weak. But since taking Omega Rejuvenol, I feel much stronger.

People comment how well I look. And I feel better, too. I would definitely recommend Omega Rejuvenol.” — Nick B., New Zealand

Martha’s vision is better!

“With Omega Rejuvenol, I first noticed my eyes. I was always putting in eye drops for dry eyes and also took cod liver oil for this. I’m not using eye drops or cod liver oil anymore.

With Omega Rejuvenol, I noticed my sight was better. I don’t have to put on my glasses to go to the bathroom at night.” — Martha, Los Angeles

Start “living younger” in 24 hours with these unique telomere-boosting breakthroughs.

It’s never too late for you to stop aging. Even if you’re 70, 80 or more, my “telomere technology” can help your body make younger cells.

Believe me, you’ll NEVER hear anything like that from the Big Pharma. That’s because keeping you younger isn’t profitable for them.

Yet if you slow the shortening of these tiny cellular clocks at the end of your DNA, your body will act years younger than your real age.

This is why my Omega Rejuvenol also includes four unique natural breakthroughs that are the best telomere boosters known to science.

Let me start with...

A little-known form of Vitamin E:
Nature’s potent “youth” vitamin

You may have heard of tocotrienols before, even if you’re not exactly sure what they are or how you can benefit from them. Who’s to blame you?

Even scientists were in the dark until a few years ago. Tocotrienols were originally misidentified and misnamed. They were lumped together with the other 7 forms of vitamin E and simply called “tocopherol.”

Just a few other doctors and I who have studied nutrition have been using these little-known isomers of vitamin E for their power to boost health.
For example, gamma tocotrienol all by itself boosts your cells’ antioxidant strength by 300%.22

But what really got my attention is how tocotrienols protect and boost telomeres.
A revealing study I found done at the University of Malaysia shows that cells given gamma tocotrienol were protected from telomere shortening. What’s more, gamma tocotrienols increased telomere lengths 16% in just 24 hours!23

Another study found that all tocotrienols, not just gamma, elongate telomere length in human cells.24

But that’s not all. Omega Rejuvenol also includes...

The telomerase supercharger

I’ve included vitamin D3 (also known as the sunshine vitamin) in Omega Rejuvenol for two important reasons.

First, it’s vital for your heart, brain, blood sugar and blood pressure. Yet 75% of U.S. adults and teens are deficient in vitamin D according to Scientific American.

More importantly, vitamin D supports healthy levels of telomerase, the enzyme that rebuild telomeres. A study showed that vitamin D supercharges telomerase activity by 19%. 25

This is why my Omega Rejuvenol includes the most natural and usable supplement form of vitamin D... vitamin D3.

Plus, you get...

The longevity vitamin

You may have heard about vitamin K2 before, but most people don’t realize how it can help you live longer and better.

Vitamin K2 is essential if you want a healthy heart, brain, bones and joints. But what it can do to fight aging is what has really caught my attention.

Vitamin K2 has been shown to have a positive effect on telomere length. This may explain the reason why people who get over 32.7 mcg daily have healthier hearts and live longer compared to those who get less than 21.6 mcg per day, according to The Rotterdam Study. 26

What’s more, you’ll also get...

The telomere extender

You know about vitamin A and its role in for healthy vision, immunity and skin. 

But Vitamin A Retinol, which I’ve included in Omega Rejuvenol, is even better.

Why? Because it’s linked to boosting the health and activity of your telomeres.

In a study reported in the Journal of Nutritional Biochemistry, women who took vitamin A as part of a multivitamin had healthier telomeres. 27

No other formula I’ve ever seen includes these four telomere boosters — and that’s why Omega Rejuvenol is my No. 1 recommended omega-3 to boost your health and longevity.

Yet there’s even more in this one-of-a-kind formula as you’ll now see...

Brigit saw an amazing effect on her pain and her quality of life and says, “I’ll always be grateful!”

Since she was a teenager, Brigit H. of Palm Springs, CA suffered from severe joint pain leading to misalignment and headaches.

She tried many things and started researching omega-3 supplements. For a while she was eating flax and chia but only got temporary relief.

But then she began taking Omega Rejuvenol, and what happened next was like a miracle.

In three months, to her shock, while she was out walking, the pain was gone. Her skin was also looking fantastic. The results in her words, “Incredible.”
Why such relief?

Because Omega Rejuvenol includes the most potent source of healing DHA I’ve ever found

Sadly, most people think fish oil is the best source of omega-3s. WRONG!

One reason I look elsewhere for omega-3s is fish oil fails to deliver enough of the most potent and vital fatty acid, DHA.

Worse, fish oil does not get into your cells quickly or deeply enough — so it can’t get to all the places it needs to be to deliver healing DHA.

Your body needs much higher amounts of DHA than it does of EPA, the other fatty acid in omega-3s.

For example, a mother’s breast milk has four times more DHA than EPA.

So I literally searched the world for a better, more concentrated source of DHA — and I found it at the end of the world!

In the icy, pure waters off the tip of South America, I found a calamarine oil derived from Argentinian squid that delivers the highest concentration of DHA ever achieved in natural medicine.

What got my attention is this mighty mollusk is loaded with DHA — at the exact same DHA to EPA ratio as mother milk: 4 to 1.

Even better, after this special squid oil is processed, it delivers more than 65% DHA — the highest amount I’ve ever seen.

Like a DHA express train

This is why I’ve added this unique super squid oil to my supercharged, super-rich Omega Rejuvenol.

Each daily serving gives you a healthy dose of squid oil (calamarine oil) making Omega Rejuvenol like a DHA express train.

To you, that can mean healthier vision, memory, blood sugar and more — not to mention telomere boosting so you live healthier and younger!

Just picture yourself with...
  • Sharper vision and healthier eyes: Studies show that people with high levels of DHA were up to 50% more likely to have healthy maculas. 28
  • A supercharged memory: Tufts University researchers report that those with high levels of DHA have a 47% lower risk of memory and brain problems. 29
  • Healthier blood sugar: DHA supports a healthier response to insulin in 70% of people taking it. 30
  • Better joint mobility: Highly absorbable DHA supports healthy joints and offers you great mobility and joint comfort. 31

Forget fish oil or ordinary omega-3 supplements. Get the most concentrated potent form of DHA omega-3s in Omega Rejuvenol!

Power up your brain with this super antioxidant

Another problem with fish oil most people don’t know is it can’t cross the blood-brain barrier.

This is tragic because your brain needs DHA omega-3s. In fact, low DHA levels are a telltale sign of an aging brain, according to a study published in Neurology.

Good news! My Omega Rejuvenol includes astaxanthin, a super antioxidant 6,000 times more powerful than vitamin C.

Astaxanthin pairs up with krill oil to cross your blood-brain barrier. The result? You get a rich supply of omega-3 DHA delivered deep into your brain cells.

In fact, in order to get a U.S. Patent, krill oil and astaxanthin had to be proven to cross the human blood-brain barrier.

Now, with krill oil and astaxanthin in my Omega Rejuvenol, you can...
  • Sharpen your thinking
  • Restore your memory
  • Learn new, complex things with ease
  • Mentally keep up with the younger generation
No wonder Sheila S. of Virginia writes, “I am happy to tell you that by taking Omega Rejuvenol, my memory has improved.”

Roger L. of California adds, “I thought I’d try Omega Rejuvenol, and it does work. My mind is now sharper.”

Memory. Energy. Vision. Skin.
For Don, age 66, everything’s better with Omega Rejuvenol!

“At age 66, I was starting to see the effects of being 66: cognitive decline, loss of energy, failing eyesight and aging skin. Today, my energy has returned, cognitive function improved, sharper eyesight and improved skin. I am very happy with Omega Rejuvenol.”
  • More get-up-and-go: “I’m 71 years old and still run my own business. Omega Rejuvenol gives me more energy and more get-up-and-go.” — Michael C., England
  • Blood pressure normal: Marc says, “I’m glad I trusted Dr. Sears and his Omega Rejuvenol. I’m so relieved to see my blood pressure is in the normal range.
  • Much less pain: “I bought Omega Rejuvenol for my wife as she had trouble with her hands. Now, in her own words, ‘I have one finger that was locking up, and it was very painful.’ After using this product, there is much less pain.” — Peter G., Australia
  • Tighter skin: “I’ve been taking Omega Rejuvenol less than 90 days, but my skin is tighter. I like it and plan to stay on it.” — Kenneth, Arizona
  • No more limping and no more fish oil: “Before I saw Dr. Sears, my old Achilles injury gave me a noticeable limp. It used to take six hours before I could walk straight. And I was taking six spoonfuls of fish oil a day. Now, with Omega Rejuvenol, my early morning shuffle is GONE, and so is my fish oil. Amazing stuff.”  David S., West Palm Beach, Florida
  • Lost memory, found: “Because of health problems, my husband lost his memory two years ago. Last month, he started taking Omega Rejuvenol and yesterday, he began remembering the past and talking a mile a minute. It was like the floodgates opened.” — Laurel T., California
  • No more fishy burps: “I just love your Omega Rejuvenol! This is the first omega-3 I can take on an empty stomach without belching up a fish taste. Within one week I started feeling improvement in my memory, and it gave me a sense of calming.” — Joy, Atlanta, Georgia

“You only need to take one Omega Rejuvenol a day to feel like you’re aging in reverse!”

Sad as it seems, most Americans don’t want to live longer.

A new survey by Pew Research Center reveals that 30% of Americans don’t want to live past age 80... and 60% don’t want to live past 90. Why?

I think it’s because they fear being debilitated in old age, withered, afflicted.

But what if you could feel a decade or younger — almost like you’re aging in reverse.

That’s exactly how you can feel using my “telomere technology” and by taking Omega Rejuvenol every day.

Help your cells (and your body) act young again

With longer telomeres, your cells behave as if they were young again. They generate more energy and fight off the plague of aging.

Over time, your body creates younger and younger cells, and when I measure telomere length, the longer telomeres correspond to a younger “biological age.”

My goal is to help you turn on telomerase... so your cells start regenerating and feeling younger.

The problem is, with short telomeres, your cells behave if they are old. As your cell age and die, you grow weaker, sicklier and more mentally foggy.

Great news! It’s never too early to begin saving your telomeres.

Join my growing band of “super agers” and create a younger version of yourself

I am grateful to be living in a time when technology allows me to help my patients and you live younger, not just longer.

The fact is, you have an advantage over everyone who has come before you.

You don’t have to let aging interfere with how you want to live.

All the people at my clinic who have been on the protocol that maintains their telomeres have had incredible health-enhancing experiences.

Their bodies, their hair, their eyesight — all better. They tell me they simply feel better. They are like “super agers.”

You may not be able to make it to my clinic in Royal Palm Beach, Florida, but now, by ordering Omega Rejuvenol, you can take the same omega-3 powerhouse my patients take and create a younger version of yourself.

Omega Rejuvenol:
Three generations ahead of any fish oil

Why is Omega Rejuvenol my No.1 omega-3 supplement — and only one I recommend to my patients and take myself?
  • It gives you nature’s most powerful telomere boosters — based on a Nobel Prize and Harvard, Yale and USC research — to help you stop aging today.
  • It gives you a special form of omega-3s — 800% better than fish oil — so you feel a whole generation younger and enjoy great cholesterol and triglycerides.
  • It gives you four youth-enhancing vitamins that help you start living younger in 24 hours.
  • It gives you the most potent source of healing DHA known to natural medicine — all to help you defy aging and supercharge your health.
  • It gives you the ultra-potent antioxidant astaxanthin — 6,000 times more powerful than vitamin C — to boost your mind and memory.
What’s more, you get all of these benefits in just one softgel a day!

You won’t risk one cent thanks to this Ironclad, Money-Back, Triple Pledge of Satisfaction

When your shipment of Omega Rejuvenol arrives, open the bottle and start taking one softgel a day. Then keep taking it knowing you won’t risk one cent. In fact, your order is backed not by one, but three guarantees...

Guarantee No. 1:

I’m confident that once you start taking Omega Rejuvenol, you will feel the difference. You will feel younger, stronger and more energized. Your satisfaction is guaranteed — or your money back!

Guarantee No. 2:

Keep taking Omega Rejuvenol, and your heart and brain will get a boost... your joints will move more effortlessly... you’ll sleep more soundly... you’ll enjoy healthy blood sugar... and you’ll feel “young again”. Your satisfaction is guaranteed — or your money back.

Guarantee No. 3:

If for any reason, or for no reason at all, you are not 100% satisfied with Omega Rejuvenol, simply return the bottle and unused portion within 90 days, and you will get an immediate, complete and total refund — including shipping and handling — with no questions asked. Your satisfaction is guaranteed — or your money back. So order today.

Three words that can help you stop aging today

Now you know these three words are: Save your telomeres!

And nothing can do that better than Omega Rejuvenol.

Now, you can use the same “telomere technology” my patients and I are using to live and feel younger, stronger and healthier — with no limits!

Get started by ordering Omega Rejuvenol today and I’ll be with you every step of the way.

To Your Good Health,


Al Sears, MD, CNS

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  2. Révész, D. et al J Clin Endocrinol Metab 2014
  3. Bojesen S., J Intern Med 2013
  4. Cawthon R.M., Lancet 2003 Feb.
  5. Devore, EE, et al. Neurosci Lett 2011 Mar
  6. Yaffe, K. et al. Neurobiol Aging 2011
  7. Wolkowitz, OM, et al PLOS One 2011 March
  8. Uchino B., Health Psychol 2012
  9. De Meyer, T et al Ageing Res Rev 2011 Apr.
  10. Haycock, P. et al BMJ (formerly British Medical Journal) 2014
  11. Buxton, JL, et al J Clin Endocrinol Metab 2011 May
  12. Terry, DE et al. Association of longer telomeres with better health in centenarians. J Gerontol A Biol Sci Med 2008 Aug
  13. Hou C, et al J Gerontol A Biol Sci Med 2011 Jun
  14. Owens DR, et al. Diabet Med 2011 Nov
  15. Rains, JL, et al. Free Radic Biol Med 2011 Mar
  16. Lin, L, et al. Nan Fang Yi Ke Da Xue Xue Bao, 2011 Mar
  17. Costenbader, KH, Autoimmun Rev 2011 Jul
  18. Kiecolt-Glaser, JK, et al. Brain Behav Immun 2013 Feb
  19. Maki, K.C. et al. Nutr Res 2009 Sept.
  20. Bunea, R. et al. Alt Med Rev 2004
  21. Mozaffarian, D., Am J Clin Nutr 2008a
  22. Nowak, G. et al. J Pharmacol Exp Ther 2011
  23. Makpol, S. et al. Oxid Med Cell Longev Jan-Feb 2010
  24. Makpol S. et al. J Biomed Biotechnol 2011
  25. Zhu H. et al. Int J. Obes (London) 2012 Jun
  26. Geleijnse, J. et al. J Nutr Nov. 2, 2004
  27. Xu, Q. et al. The Am J Clin Nutr June 2009
  28. Fosshaug, L.E. et al. Lipids in Health and Disease, Dec 29, 2011
  29. Am J. Clin Nutr 2008 May
  30. Fish Oil Supplement Guide, Environmental Defense Fund, 2009
  31. Deutsch, L. J Am Coll Nutr 2007 Feb